Glutathione for Injection
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CAS No.: 70-18-8
TYPE: JP GRADE & USP GRADE
BRAND: ZNCBIO
MOQ: 20 KGS
Introduction of Glutathione for Injection
Glutathione for injection is a commonly used high-end medical antioxidant and liver-protecting preparation in clinical practice. It is refined from high-purity sterile raw materials and belongs to the endogenous active peptide substances naturally present in the human body.
This product possesses strong antioxidant, detoxification and cell repair capabilities. It can efficiently eliminate free radicals in the body, alleviate oxidative stress damage, and stabilize the integrity of cell membranes. At the same time, it can significantly enhance the liver’s metabolic and detoxification capabilities, neutralize harmful substances such as drugs, alcohol, chemical toxins and heavy metals, repair damaged liver cells, and improve liver function.
It is suitable for the auxiliary treatment of drug-induced, alcoholic, toxic liver damage and various liver diseases, and can also be used for the regulation of overall oxidative stress damage. The product has high purity, good safety, and quick onset of action. It strictly follows the pharmaceutical injection-grade production standards and is safe and reliable for clinical application.
Basic Information of Glutathione for Injection
| Items | Results |
|---|---|
| Formula | C10H17N3O6S |
| Molecular Weight | 307.32 |
| Solubility | 41 mg/mL in water |
| Storage | 2-8°C, dry, protect from light, sealed |
| QC Standard | 99.86% |
| H-NMR | Consistent with structure |
Function of Glutathione for Injection
Glutathione for injection is a naturally occurring active tripeptide substance in the human body. It is administered intravenously or intramuscularly to directly enter the bloodstream, with rapid onset and high bioavailability. Its clinical efficacy is clear and comprehensive:
1. Strong antioxidant, providing comprehensive protection for cells
Strongly eliminates excessive oxygen free radicals and peroxides in the body, inhibits lipid peroxidation reactions, reduces systemic oxidative stress damage. Stabilizes cell membrane structure, reduces the aging and damage risks of organ cells and tissues, repairs oxidative-induced systemic damage, and maintains the normal redox balance of the body.
2. Core liver detoxification, repairing liver damage
Enhances the second-phase detoxification metabolic function of the liver, combines and neutralizes alcohol, chemical toxins, heavy metals, drug toxins, and harmful metabolic substances, accelerates toxin decomposition and excretion. It can significantly repair alcoholic, drug-induced, toxic, and viral liver damage, reduce transaminase levels, alleviate liver cell inflammation, necrosis, and fibrosis, and improve overall liver function.
3. Detoxification and anti-poisoning, clinical emergency assistance
For scenarios such as chemical toxins, heavy metals, drug overdose, and chemical poisoning, it exhibits broad-spectrum detoxification effects, reducing the continuous damage of toxins to the liver, kidneys, blood, and multiple organs. It is an important drug for clinical poisoning rescue.
4. Regulate immunity, enhance body defense
Protects immune cells from oxidative damage, maintains the activity of lymphocytes and immune cells, regulates the body’s immune function, reduces inflammatory responses, enhances physical resistance, and reduces immune deficiency problems caused by severe diseases, postoperative recovery, and chronic diseases.
5. Anti-aging and brightening, improving metabolic state
Inhibits excessive melanin production, reduces pigmentation, improves dark skin, pigmentation, and uneven skin tone; at the same time, improves microcirculation and energy metabolism throughout the body, alleviates fatigue, weakness, and other symptoms caused by severe diseases, chronic diseases, and postoperative recovery, and assists in improving sub-health conditions of the body.
6. Protection of multiple organs, reducing complication risks
It has protective effects on important organs such as the kidneys, heart, lungs, and digestive tract mucosa. It can alleviate the side effects of radiotherapy, chemotherapy, and long-term medication on organs, reduce complications induced by oxidative stress, and is suitable for intensive care, postoperative recovery, and radiotherapy-assisted conditioning.
Application of Glutathione for Injection
Glutathione for injection is a naturally occurring active tripeptide substance in the human body. It is administered intravenously or intramuscularly to directly enter the bloodstream, with rapid onset and high bioavailability. Its clinical efficacy is clear and comprehensive:
1. Strong antioxidant, providing comprehensive protection for cells
Strongly eliminates excessive oxygen free radicals and peroxides in the body, inhibits lipid peroxidation reactions, reduces systemic oxidative stress damage. Stabilizes cell membrane structure, reduces the aging and damage risks of organ cells and tissues, repairs oxidative-induced systemic damage, and maintains the normal redox balance of the body.
2. Core liver detoxification, repairing liver damage
Enhances the second-phase detoxification metabolic function of the liver, combines and neutralizes alcohol, chemical toxins, heavy metals, drug toxins, and harmful metabolic substances, accelerates toxin decomposition and excretion. It can significantly repair alcoholic, drug-induced, toxic, and viral liver damage, reduce transaminase levels, alleviate liver cell inflammation, necrosis, and fibrosis, and improve overall liver function.
3. Detoxification and anti-poisoning, clinical emergency assistance
For scenarios such as chemical toxins, heavy metals, drug overdose, and chemical poisoning, it exhibits broad-spectrum detoxification effects, reducing the continuous damage of toxins to the liver, kidneys, blood, and multiple organs. It is an important drug for clinical poisoning rescue.
4. Regulate immunity, enhance body defense
Protects immune cells from oxidative damage, maintains the activity of lymphocytes and immune cells, regulates the body’s immune function, reduces inflammatory responses, enhances physical resistance, and reduces immune deficiency problems caused by severe diseases, postoperative recovery, and chronic diseases.
5. Anti-aging and brightening, improving metabolic state
Inhibits excessive melanin production, reduces pigmentation, improves dark skin, pigmentation, and uneven skin tone; at the same time, improves microcirculation and energy metabolism throughout the body, alleviates fatigue, weakness, and other symptoms caused by severe diseases, chronic diseases, and postoperative recovery, and assists in improving sub-health conditions of the body.
6. Protection of multiple organs, reducing complication risks
It has protective effects on important organs such as the kidneys, heart, lungs, and digestive tract mucosa. It can alleviate the side effects of radiotherapy, chemotherapy, and long-term medication on organs, reduce complications induced by oxidative stress, and is suitable for intensive care, postoperative recovery, and radiotherapy-assisted conditioning.
Glutathione for Injection Compared with Other Forms of Glutathione
1. Core Essence Definition
The injectable form of glutathione mostly refers to reduced glutathione (GSH), the original active form in the human body, which possesses antioxidant, detoxification, and liver-protecting activities. It is administered by injection and takes effect the fastest in clinical settings.
The oxidized form of glutathione (GSSG) is the inactive form resulting from the oxidation of two reduced GSH molecules. It has no direct antioxidant effect and requires reduction in the body to be effective. It is a metabolic intermediate.
S-acetyl-L-glutathione (SAG) is a modified derivative of reduced GSH with an acetyl group protecting the active site, designed specifically for oral administration and offering a stable improved version.
2. Differences in Structure and Stability
Injectable reduced GSH
The active thiol group is intact, with the strongest activity; however, it is extremely unstable and prone to oxidation and loss of activity upon exposure to acids, high temperatures, and oxygen. It cannot be taken orally and can only be administered by injection.
Oxidized GSSG
The thiol group is oxidized and closed, with a stable structure, but it has no direct biological activity and requires energy consumption in the body for activation.
S-acetyl-L-glutathione SAG
The acetyl group protects the active site, making it resistant to stomach acid, digestive enzymes, and oxidation. It has extremely strong stability and is suitable for oral absorption.
3. Absorption Method and Bioavailability
Injectable glutathione
Intravenous / Intramuscular injection, directly enters the bloodstream, 100% absorption, immediate effect, highest utilization rate in medical grade.
Oxidized glutathione
Oral absorption is generally poor, and it requires secondary reduction activation in the body, with limited conversion efficiency, and overall utilization rate is low.
S-acetyl-L-glutathione
Oral absorption can pass through the stomach and intestines intact, and after entering the cells, it automatically deacetylates and converts into active GSH, addressing the deficiency of ordinary GSH in oral absorption, and is the optimal form for oral use.
4. Strength of Efficacy and Characteristics of Action
Injectable reduced GSH
The strongest efficacy, direct and potent: rapid liver protection and detoxification, emergency detoxification, repair of liver damage, protection of organs during radiotherapy and chemotherapy, and emergency treatment for severe cases. It is at the medical treatment level.
Oxidized GSSG
The effect is mild and takes effect indirectly, with weak antioxidant capacity, mostly used for cell culture, biochemical reagents, and auxiliary addition in formulations, and rarely as an efficacy supplement material.
S-acetyl-L-glutathione
The effect is mild and long-lasting, focusing on daily antioxidant, internal use whitening, liver care, adjustment of sub-health, and skin care raw materials, and is of health and beauty grade.
5. Differences in Application Domains
Injectable glutathione
Hospital clinical, hepatology department, emergency department, oncology department, medical aesthetic infusion, poisoning emergency treatment, postoperative rehabilitation, pharmaceutical grade, injection grade.
Oxidized glutathione
Biological research reagents, cell culture medium, biochemical experiments, cosmetic auxiliary additives, rarely used as a supplement for health or medicine.
S-acetyl-L-glutathione
Dietary supplements, oral whitening products, functional foods, high-end skin care raw materials, cross-border health care raw materials, food grade / cosmetic grade.
7. Summary of Safety and Usage Scenarios
Injectable GSH: Medical treatment, quick effect, requires professional operation, suitable for pathological damage, severe cases, and emergency treatment.
Oxidized GSSG: No direct activity, more of a research reagent, not recommended as a supplement.
SAG (S-acetyl): Daily long-term oral use, safe and mild, good absorption, suitable for daily maintenance of health, whitening, liver care.
Contact Details
SHANGHAI ZNCBIO
Precautions for Glutathione for Injection
1. Attention on Allergy-related Issues
Those who are allergic to glutathione, the ingredients of this product or similar polypeptide drugs must not use it. It may cause allergic rashes, itching, laryngeal edema, breathing difficulties, and in severe cases, allergic shock.
People with allergic constitution and those with a history of multiple drug allergies should use it with caution. Prepare for emergency treatment before administration, and closely monitor the body’s reactions during the initial stage of use.
2.Caution for Special Populations
Pregnant and lactating women： Limited clinical safety data is available. Unless the benefits outweigh the risks as assessed by a doctor， it is not recommended to use at will.
Children and the elderly： With weak liver and kidney functions， the dosage should be reduced according to age and weight. Follow the doctor’s instructions strictly and do not adjust the dosage on your own.
Patients with severe renal insufficiency， end-stage severe liver disease， and severe heart and lung failure should use it with caution to prevent aggravation of organ burden due to metabolic accumulation.
3. Administration and Incompatibility
This product is an injection preparation and can only be administered by intravenous drip， intravenous injection， or intramuscular injection. It is prohibited to be taken orally. Other improper administration methods are strictly forbidden.
It is strictly prohibited to mix with strong oxidants or alkaline drugs， as this will destroy the molecular structure， leading to loss of efficacy， precipitation， or the production of harmful substances.
The solution should be prepared and infused separately. It is not recommended to share the infusion tubing with other injection solutions to avoid chemical reactions.
The prepared solution should be used immediately and should not be stored for a long time， exposed to light， or kept at high temperatures to prevent drug oxidation， color change， loss of activity， and microbial contamination.
4. Monitoring of Adverse Reactions
Some people may experience nausea， vomiting， dizziness， headache， and mild gastrointestinal discomfort after using this product. The symptoms are usually mild and can be relieved after discontinuation of the medication.
If abnormal reactions such as chills， fever， chest tightness， palpitations， or generalized skin rashes occur， the medication should be stopped immediately and appropriate emergency treatment should be taken.
Long-term and high-dose continuous use requires regular monitoring of liver and kidney functions and blood routine to avoid long-term abuse causing metabolic disorders.
5. Clinical Use Specifications
This product is a medical prescription preparation and cannot be administered orally as a regular health supplement. It should be used under the professional medical care of a medical institution.
It is only for auxiliary treatment of diseases and cannot replace antiviral， liver-protecting special drugs， or symptomatic treatment drugs. It should not be relied on solely for the treatment of liver diseases or severe diseases.
6. Storage and Transportation Notes
Store the solution in a sealed container in a cool， dark， dry， and low-temperature environment. Keep it away from heat sources， direct sunlight， and freezing environments.
During transportation， avoid violent shaking， squeezing， and prevent the bottle from breaking or the drug solution from leaking to ensure the integrity and stability of the drug.
7. Other Important Notes
If the solution shows any signs of deterioration such as discoloration， turbidity， precipitation， or foreign substances， it should not be used.
When used in combination with radiotherapy， poisoning emergency treatment， or postoperative patients， the doctor should assess the drug interactions uniformly and plan the dosage intervals and doses reasonably.
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Shanghai ZNC Biotechnology Co., Ltd.(ZNCBIO) is a supplier of various chemicals and packaging materials. In addition to Glutathione for Injection、S-Acetyl-L-Glutathione、Oxidized Glutatione , it can also provide you with products in many fields such as nutritional supplements, food additives, APIs, cosmetics and minerals.
