Prodcut name: Natural Pure Orange Peel Extract Diosmin
Diosmin:Hesperidin = 90:10
Specification: Diosmin 90 : 10 hesperidine
Appearance: Off white fine powder
Mesh size: 80 Mesh
Used Part: fruit
Grade: Pharmaceuticals Ingredients
Diosmin (diosmetin 7-O-rutinoside), a flavone derivative also known as venosmine, is a glycoside of diosmetin, which in turn is the 4'-methoxy derivative of luteolin. Diosmin is naturally occurring, mainly in the citrus family rutaceae, but also in herbs such as Teucrium gnaphalodes.
Diosmin is used to enhance intravenous tension drugs and vasodilators.First of all for the venous system, this product through extension.The adrenalin ACTS on the vein wall to cause the contraction of time, thereby enhancing the intravenous tension;For microcirculation system, this product can reduce the permeability of capillaries and enhance their resistance.For the lymphatic system, this product increases lymphatic drainage speed and lymphatic contraction, improves lymphatic reflux and reduces edema.
1.Diosmin prolongs the vasoconstrictor effect of norepinephrine on the vein wall, increasing venous tone, and therefore reducing venous capacitance, distensibility, and stasis.
2.Diosmin increases the venous return and reduces venous hyperpressure present in patients suffering from CVI.
3.Diosmin improves lymphatic drainage by increasing the frequency and intensity of lymphatic contractions, and by increasing the total number of functional lymphatic capillaries.
4.Diosmin with hesperidine decreases the diameter of lymphatic capillaries and the intralymphatic pressure.
5.At the microcirculation level, diosmin reduces capillary hyperpermeability and increases capillary resistance by protecting the microcirculation from damaging processes.
6.Diosmin reduces the expression of endothelial adhesion molecules,and inhibits the adhesion, migration, and activation of leukocytes at the capillary level.Diosmin leads to a reduction in the release of inflammatory mediators, principally oxygen free radicals and prostaglandins.
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